| Primary Identifier | MGI:5704132 | Allele Type | Targeted |
| Attribute String | Hypomorph | Gene | Cacna1a |
| Transmission | Germline | Strain of Origin | C57BL/6 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An F1406C mutation (c.4486T>G) was introduced into exon 26 and a floxed neo cassette was inserted downstream of exon 26 via homologous recombination. Cre mediated recombination removed the neo cassette. Homozygous mice display a ~70% reduction in Cav2.1 current density in Purkinje cells. |
