| Primary Identifier | MGI:5705582 | Allele Type | Transgenic |
| Attribute String | Inducible, Knockdown, Recombinase | Gene | Tg(Itgam-cre/ERT2,U6-RNAi:Cacna1b)17Ttan |
| Strain of Origin | C57BL/6J | Induced With | tamoxifen |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | The transgene is composed of the human RNU6 promoter disrupted by a floxed neomycin resistance cassette, short-hairpin RNA targeting Cacna1b, the human GH sequence, and the mouse Itgam promoter driving expression of an inducible cre recombinase gene (cre/ERT2) in microglial/macrophage cells. Five founders were generated and line 17 was selected as the representative line. |
