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Allele : Cdk4<tm2.2Bbd> cyclin dependent kinase 4; targeted mutation 2.2, Mariano Barbacid

Primary Identifier  MGI:5705761 Allele Type  Targeted
Attribute String  Conditional ready Gene  Cdk4
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  An frt site was inserted 230 bp upstream of exon 2 and a frt-flanked hygromycin resistance cassette 115 bp downstream of exon 4 in ES cells already carrying the Cdk2tm2.1Sgo conditional mutation of Cdk2 and integrated into the same chromosome. The selection cassette was excised by Flp-mediated recombination, leaving exons 2-4 flanked by frt sites.
  • mutations:
  • Insertion
  • synonyms:
  • Cdk4<frt>,
  • Cdk4<frt>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories