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Allele : Retsat<tm1Kpal> retinol saturase (all trans retinol 13,14 reductase); targeted mutation 1, Krzysztof Palczewski

Primary Identifier  MGI:5708113 Allele Type  Targeted
Attribute String  Null/knockout Gene  Retsat
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 1 was replaced with a neomycin selection cassette. RT-PCR of RNA isolated from the liver of homozygous mice using primers directed against exon 1 and exon 4 shows that there was no detectable message expressed from this allele. Immunoblotting of liver lysates and immunohistochemistry of liver sections from homozygous mice indicates that the encoded protein is not detectable in homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • RetSat<->,
  • RetSat<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele