| Primary Identifier | MGI:5708562 | Allele Type | Targeted |
| Gene | Des | Transmission | Germline |
| Strain of Origin | 129 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | An R349P mutation (AGG to CCC) was inserted in exon 6 and a floxed neo cassette was inserted in intron 6 via homologous recombination. Cre mediated recombination removed the neo cassette. Immunoblot analysis indicates severely reduced expression of the mutant protein. |
