Primary Identifier | MGI:5749963 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(Myh6-cre/ERT2/Hif1a)#Hhas |
Strain of Origin | C57BL/6 x C3H | Induced With | tamoxifen and hypoxia |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The transgene contains the Myh6 promoter that drives cardiac-specific expression of the inducible cre recombinase gene (cre/ERT2) fused with the oxygen-dependent degradation (ODD) domain of Hif1a. This transgene is responsive to hypoxia. The pound symbol (#) is used when no line is specified and/or lines are pooled. |