| Primary Identifier | MGI:5708657 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Abcb10 |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Cre-mediated recombination removed the loxP flanked exon 3, causing a frameshift mutation at the splice junction site across exons 2 and 4. This results in disruption of 3 transmembrane motifs and an ATP-binding domain that is encoded by the downstream region of exon 3. Western blot analysis confirmed absence of protein in homozygotes. |
