| Primary Identifier | MGI:5708839 | Allele Type | Transgenic |
| Attribute String | Inducible, Inserted expressed sequence, Reporter | Gene | Tg(tetO-lacZ,-GFP/Gria2)6Rsp |
| Strain of Origin | C57BL/6 or DBA | Induced With | doxycycline/tetracycline |
| Is Recombinase | false | Is Wild Type | false |
| description | "Mouse lines TgTetOGFP-GluA2/1 and TgTetOGFP-GluA2/6 are derived from two diffferent founders from the same pronucleus injection" (J:82809). The transgenic construct was microinjected into the pronuclei of oocytes obtained from either "DBA1/C57Bl/6 F1 hybrids" (J:103689) or (C57BL/6 x DBA/2)F1 mice (J:82809). |
| molecularNote | This transgene contains a tetracycline responsive element, comprising seven tandem copies of the tetracycline operator (tetO), driving bidirectional expression of beta-galactosidase (from the lacZ gene) with a nuclear localization signal and of a green fluorescent protein/rat glutamate receptor, ionotropic, AMPA2 (alpha 2) (GFP/Gria2) fusion protein; the GFP coding sequence is preceded by the signal sequence of the Drosophila cuticle protein C3 and the Myc epitope tag. |
