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Allele : Ar<tm5.1(AR*)Dmr> androgen receptor; targeted mutation 5.1, Diane M Robins
Primary Identifier  MGI:5749486 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Ar
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  Human androgen receptor amino acids 31 to 484 were inserted into the mouse locus. This allele contains 113 glutamine residues in the N terminal and K385R (AAG to AGA) and K518R (AAA to CGA) mutations. A floxed neo cassette was also inserted via homologous recombination. Cre mediated recombination removed the neo cassette.
  • mutations:
  • Nucleotide repeat expansion,
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • AR113Q-KRKR,
  • AR113Q-KRKR
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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