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Allele : Scn2a<tm1.1Spet> sodium channel, voltage-gated, type II, alpha; targeted mutation 1.1, Steven Petrou

Primary Identifier  MGI:5749565 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Scn2a
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
description  ES cell line = B6-White in J:219222
molecularNote  A floxed neo cassette was inserted upstream of exon 4 and a mutant exon 5N with 4 point mutations that create an N209D substitution and an AccI restriction site was inserted via homologous recombination. Cre mediated recombination removed the neo cassette. This mutation converts the neonatal specific exon sequence so that it matches that of the adult specific exon 5A.
  • mutations:
  • Insertion
  • synonyms:
  • Nav1.2<adult>,
  • Nav1.2<adult>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories