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Publication : Nucleolar protein 1 (Nol1) expression in the mouse brain.

First Author  Mitrecić D Year  2008
Journal  Coll Antropol Volume  32 Suppl 1
Pages  123-6 PubMed ID  18405070
Mgi Jnum  J:226523 Mgi Id  MGI:5697623
Citation  Mitrecic D, et al. (2008) Nucleolar protein 1 (Nol1) expression in the mouse brain. Coll Antropol 32 Suppl 1:123-6
abstractText  Nucleolar protein 1 (Nol1) is a cell cycle dependent gene highly expressed in proliferating tissues. In order to test whether Nol1 could be used as a marker of dividing neural stem cells within mouse brain, Nol1 expression was analyzed using mouse carrying a gene trap modification of Nol1 gene. High Nol1 expression was found within the hippocampus, olfactory bulb, cerebral and cerebellar cortex. Nol1 was expressed not only in the dividing cells within the brain, but as well in the postmitotic neurons. This suggested a general role of Nol1 in assembling of ribosomes in cells with high protein production.
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