Primary Identifier | MGI:5750308 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene |
Tg(CD68-H2-Ab1)#Rhd |
Strain of Origin | (B10.P-H2<p>/SgTuRhd x C3H.NB-H2<p>/SnTuRhd)F2 | Is Recombinase | false |
Is Wild Type | false |
description | MBQ is used by the transgene's creators to refer specifically to a strain in which "macrophages exclusively expressed the MHC class II H2-Aq (Aq) on an H2-Ap (Ap) background." (J:175428) |
molecularNote | This transgene contains the human macrophage-specific CD68 promoter through the splice signal flanking the first intron followed by the coding sequence of the mouse MHC class II H2-Ab1q allele. Expression is strain dependent. |