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Allele : Tg(CD68-H2-Ab1<q>)#Rhd transgene insertion, Rikard Holmdahl

Primary Identifier  MGI:5750308 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(CD68-H2-Ab1)#Rhd
Strain of Origin  (B10.P-H2<p>/SgTuRhd x C3H.NB-H2<p>/SnTuRhd)F2 Is Recombinase  false
Is Wild Type  false
description  MBQ is used by the transgene's creators to refer specifically to a strain in which "macrophages exclusively expressed the MHC class II H2-Aq (Aq) on an H2-Ap (Ap) background." (J:175428)
molecularNote  This transgene contains the human macrophage-specific CD68 promoter through the splice signal flanking the first intron followed by the coding sequence of the mouse MHC class II H2-Ab1q allele. Expression is strain dependent.
  • mutations:
  • Insertion
  • synonyms:
  • MBQ,
  • Macrophage A beta Q,
  • MBQ,
  • Macrophage A beta Q
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories