| Primary Identifier | MGI:5750743 | Allele Type | Targeted |
| Attribute String | Conditional ready, Inserted expressed sequence | Gene | Syk |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site, splice acceptor site, wild-type mouse Syk cDNA, FRT flanked neo cassette, loxP site, splice acceptor site, and exon 2 with an R41A mutation were inserted via homologous recombination. In the absence of cre mediated recombination the wild-type gene is expressed. Following cre mediated recombination a mutant protein lacking binding to phosphotyrosine at the N-terminal SH2 is expressed. |
