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Allele : Itk<tm1.1Gsk> IL2 inducible T cell kinase; targeted mutation 1.1, GlaxoSmithKline

Primary Identifier  MGI:5750989 Allele Type  Targeted
Gene  Itk Transmission  Germline
Strain of Origin  BALB/c Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 12 was replaced with a floxed, modified exon 12 in which nucleotide substitution results in the amino acid substitution of arginine for lysine at position 390 (K390R). Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of the modified exon 12.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Itk<K390R>,
  • Itk<K390R>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories