Primary Identifier | MGI:5750989 | Allele Type | Targeted |
Gene | Itk | Transmission | Germline |
Strain of Origin | BALB/c | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 12 was replaced with a floxed, modified exon 12 in which nucleotide substitution results in the amino acid substitution of arginine for lysine at position 390 (K390R). Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of the modified exon 12. |