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Allele : **Tg(Prnp-rtTA2S*M2)#Rkhu** transgene insertion, Renate K Hukema

Primary Identifier	MGI:5751867	Allele Type	Transgenic
Attribute String	Transactivator	Gene	*Tg(Prnp-rtTA2SM2)#Rkhu**
Strain of Origin	C57BL/6JRj	Is Recombinase	false
Is Wild Type	false

molecularNote

The prion protein promotor drives the expression of the rtTA2S-M2 variant in the central nervous system (both neurons and glia cells).

mutations:
Insertion

synonyms:
Prp-rtTA,
Prp-rtTA

earliestPublication:
Hukema RK, et al. (2015) Reversibility of neuropathology and motor deficits in an inducible mouse model for FXTAS. Hum Mol Genet 24(17):4948-57

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

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Allele : Tg(Prnp-rtTA2S*M2)#Rkhu transgene insertion, Renate K Hukema

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