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Allele : Igh<tm10.1Fwa> immunoglobulin heavy chain complex; targeted mutation 10.1, Frederick W Alt

Primary Identifier  MGI:5752253 Allele Type  Targeted
Gene  Igh Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  In intergenic control region 1 (IGCR1) the second CCCTC-binding factor (CTCF)-binding element (CBE2) was replaced with scrambled sequence that does not bind CTCF. A floxed neo cassette was also inserted between the two CBEs and subsequently removed by cre mediated recombination.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • IGCR1/CBE2<->,
  • IGCR1/CBE2<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories