Primary Identifier | MGI:5752179 | Allele Type | Targeted |
Gene | Aoc3 | Transmission | Germline |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A point mutation was introduced that changes an amino acid in the active site from Tyr to Phe. This disrupts semicarbazide-sensitive amine oxidase activity. Immunohistochemical analysis indicates that the expression pattern of the mutant protein is similar to wild-type. |