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Allele : Tg(CD68-Prkaa1*T172D)1Dbrh transgene insertion 1, DeBroski R Herbert

Primary Identifier  MGI:5752355 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(CD68-Prkaa1*T172D)1Dbrh
Strain of Origin  C57BL/6NTac Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene was designed to have the human CD68-IVS-1 promoter (~1 kbp of human CD68 5' flanking sequence with the 83 bp first intron enhancer [IVS-1])direct expression of an AMP-activated protein kinase catalytic alpha 1 cDNA sequence harboring the constitutively active threonine 172 to aspartic acid amino acid substitution (T172D) with amino-terminal myc epitope tag, all followed by a polyadenylation signal. The investigator does not indicate organism source of the expressed gene (e.g. human, mouse, etc.).
  • mutations:
  • Insertion
  • synonyms:
  • huCD68-AMPKalpha1<T172D>,
  • CD68-AMPKTG,
  • CD68-AMPKTG,
  • huCD68-AMPKalpha1<T172D>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

2 Publication categories