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Allele : Spp1<tm1.1Cant> secreted phosphoprotein 1; targeted mutation 1.1, Harvey Cantor
Primary Identifier  MGI:5752396 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Spp1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  45 nucleotides in exon 2 after the start codon that encode an N-terminal signal sequence were deleted. A floxed stop and neomycin resistance cassette was inserted upstream of the modified exon 2. Cre-mediated recombination removed the floxed stop selection cassette. Western blot analysis confirmed expression of only the intracellular isoform in splenocyte.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • OPN-i-KI,
  • OPN-i-KI
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

4 Publication categories





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