| Primary Identifier | MGI:5754390 | Allele Type | Transgenic |
| Attribute String | Inducible, Inserted expressed sequence, Reporter | Gene | Tg(tetO-Gja1,-EGFP)L11Kwi |
| Strain of Origin | C57BL/6 or FVB/N | Induced With | doxycycline/tetracycline |
| Is Recombinase | false | Is Wild Type | false |
| description | The transgene construct was microinjected into C57BL/6 x FVB/N fertilized oocytes. (J:82809) |
| molecularNote | The transgene contains the tetracycline response element, comprising seven copies of the tetracycline operator (tetO) sequence, flanked on each side by a cytomegalovirus (CMV) minimal promoter and the coding sequence for either gap junction protein, alpha 1 (Gja1, also called Cx43) or enhanced green fluorescent protein (EGFP), each followed by the beta-globin insulator sequence. Expression of the tetracycline transactivator from a second transgene result in the expression of both Gja1 and the EGFP reporter. |
