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Allele : Tg(PRNP)35Jcol transgene insertion 35, John Collinge
Primary Identifier  MGI:5760243 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(PRNP)35Jcol
Strain of Origin  mixed Is Recombinase  false
Is Wild Type  false
description  This transgene was originally microinjected into Prnptm1Cwe oocytes. Oocytes of mixed background involve: 129 * C57BL/6 * FVB/N.
molecularNote  This transgene consists of the human PRNP with methionine at codon 129, a polymorphism determining susceptibility to sporadic and acquired prion diseases.
  • mutations:
  • Insertion
  • synonyms:
  • 129MM Tg35,
  • 129MM Tg35,
  • Tg(HuPrP129M),
  • Tg(HuPrP129M)
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

3 Publication categories





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