Primary Identifier | MGI:5755092 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Tox3 |
Strain of Origin | C57BL/6NCrl | Is Recombinase | false |
Is Wild Type | false | Project Collection | IMPC |
molecularNote | This allele produced from project TCPR0331 at TCP by injecting Cas9 mRNA and one guide RNA with the spacer sequence GGGAAGGCAACGGATCGCTG. This resulted in a 4 bp deletion from Chr8:90270347 to 90270350 in ENSMUSE00000331868. This mutation is predicted to cause a frameshift with amino acid changes after residue 96 and early truncation 53 amino acids later (p.S96Rfs*55). (GRCm38). |