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Allele : Tox3<em1(IMPC)Tcp> TOX high mobility group box family member 3; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:5755092 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Tox3
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele produced from project TCPR0331 at TCP by injecting Cas9 mRNA and one guide RNA with the spacer sequence GGGAAGGCAACGGATCGCTG. This resulted in a 4 bp deletion from Chr8:90270347 to 90270350 in ENSMUSE00000331868. This mutation is predicted to cause a frameshift with amino acid changes after residue 96 and early truncation 53 amino acids later (p.S96Rfs*55). (GRCm38).
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele