| Primary Identifier | MGI:5755302 | Allele Type | Targeted |
| Attribute String | Hypomorph | Gene | Jup |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A floxed neomycin resistance cassette was inserted upstream of exon 10. Exon 11 was replaced with a modified one in which a TG were deleted. This mutation mimics the mutation found in patients with Naxos disease and results in a premature stop codon in exon 12. Flp-mediated recombination removed the selection cassette. RT-PCR confirmed reduced transcript expression. |
