Primary Identifier | MGI:5763089 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(Mbp-icre/ERT2)#Rjfl |
Strain of Origin | (C57BL/6 x CBA)F1 | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The transgenic mouse strain was made using small plasmid transgenesis. A 5.89-Kbp upstream region of Mbp (promoter fragment) was used for driving iCreERT2 with parts of Plp exons 6 and 7 downstream, followed by a poly(A) sequence. Two founders were obtained, and as both had similar expression patterns and intensity, one was selected for further characterization. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled. |