|  Help  |  About  |  Contact Us

Allele : Kl<ecalc1> klotho; ectopic calcification 1

Primary Identifier  MGI:5763757 Allele Type  Chemically induced (ENU)
Attribute String  Hypomorph Gene  Kl
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  ENU mutagenesis induced a C to T transition in exon 1 that results in the generation of a stop codon at position 203. This mutation, located in the KL1 domain, is severely hypomorphic and leads to a 17-fold reduction in renal expression, as determined by qRT-PCR analysis.
  • mutations:
  • Single point mutation
  • synonyms:
  • kl<203X>,
  • kl<203X>,
  • kl<Q203X>,
  • kl<Q203X>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories