Primary Identifier | MGI:5765989 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(ACTA1-Ctss)1Jmol |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene consists of a Ctss cDNA sequence under the control of a modified human ACTA1 promoter, which is active in skeletal muscle. Western blot analysis confirms overexpression in multiple skeletal muscles that are predominantly fast-twitch, with lower levels of expression in soleus (slow-twitch). Founder line 1 is the higher expressing transgenic line. |