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Allele : Tg(Ckm-DNAJB6_ib*F93L)#Ccwe transgene insertion, Conrad C Weihl

Primary Identifier  MGI:5767288 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Ckm-DNAJB6_ib*F93L)#Ccwe
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The human wild-type DNAJB6 isoform b with the most common Limb-girdle muscular dystrophy type 1D mutation, F93L, and with N-terminal V5 tags is under the control of the muscle-specific muscle creatine kinase promoter. Immunoblot analysis confirmed expression exclusively in skeletal muscle and not in heart, liver, kidney, or brain. Three lines were generated, however the pound symbol (#) is used when line is not specified and/or lines are pooled.
  • mutations:
  • Insertion
  • synonyms:
  • hDNAJB6a-F93L,
  • hDNAJB6a-F93L
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories