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Allele : Fen1<tm4.1Bhsh> flap structure specific endonuclease 1; targeted mutation 4.1, Binghui Shen
Primary Identifier  MGI:5767325 Allele Type  Targeted
Gene  Fen1 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The coding sequence was replaced with a floxed neomycin resistnace cassette and a modified coding sequence in which a C to T point mutation results in the amino acid substitution of valine for alanine at position 159 (A159V). This mutation has been observed in human cancers. Cre-mediated recombination removed the selection cassette.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Fen1<A159V>,
  • Fen1<A159V>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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3 Publication categories

Trail: Allele




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