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Allele : Nod2<tm1.1Mpdy> nucleotide-binding oligomerization domain containing 2; targeted mutation 1.1, Michael P Davey

Primary Identifier  MGI:5767092 Allele Type  Targeted
Gene  Nod2 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 4 was replaced with an FRT-flanked neomycin resistance cassette and a modified exon 4 in which a G to A point mutation results in the amino acid substitution of glutamine for arginine at position 314 (R314Q). Flp-mediated recombination removed the selection cassette.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • R314Q-Nod2 KI,
  • R314Q-Nod2 KI
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories