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Allele : Trem2<em1Adiuj> triggering receptor expressed on myeloid cells 2; endonuclease-mediated mutation 1, MODEL-AD Center
Primary Identifier  MGI:5770794 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Trem2
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  The allele was generated by injecting cas9 nuclease and a single guide RNA designed to introduce a R47H point mutation with two silent mutations (lysine AAG>AAA and alanine GCC>GCA) into the gene.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Trem2 R47H KI,
  • Jax R47H ki,
  • Jax R47H ki,
  • Trem2 R47H KI
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

34 Carried By

0 Driven By

19 Publication categories





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