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Allele : Nat8l<tm1.1Meck> N-acetyltransferase 8-like; targeted mutation 1.1, Matthias Eckhardt

Primary Identifier	MGI:5771690	Allele Type	Targeted
Attribute String	Conditional ready, No functional change, Reporter	Gene	Nat8l
Transmission	Germline	Strain of Origin	129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase	false	Is Wild Type	false

molecularNote

Exon 3 was flanked by loxP sites and a loxP/FRT-flanked neomycin resistance gene followed by an IRES-lacZ cassette were inserted downstream of exon 3 via homologous recombination. The neomycin selection cassette was removed via Flp-mediated recombination

mutations:
Insertion

cellLines:
Not Specified

earliestPublication:
Maier H, et al. (2015) N-Acetylaspartate Synthase Deficiency Corrects the Myelin Phenotype in a Canavan Disease Mouse Model But Does Not Affect Survival Time. J Neurosci 35(43):14501-16

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

6 Publication categories

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