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Allele : Mapt<tm2(FUS)Neas> microtubule-associated protein tau; targeted mutation 2, Neil A Shneider

Primary Identifier  MGI:5776260 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence Gene  Mapt
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed STOP cassette and a modified human cDNA in which nucleotide substitutions resulted in the amino acid substitution of cysteine for arginine at position 521 (R521C) with a myc-tag replaced the 3' portion of exon 2. Cre-mediated recombination is required to remove the stop cassette and allow for expression of the human sequence.
  • mutations:
  • Insertion,
  • Nucleotide substitutions,
  • Intragenic deletion
  • synonyms:
  • tau<OFF>hFUS<R521C>,
  • tau<OFF>hFUS<R521C>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories