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Allele : Pik3ca<tm1.1Rps> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 1.1, Ramon Parsons
Primary Identifier  MGI:5776387 Allele Type  Targeted
Attribute String  Not Specified Gene  Pik3ca
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 9 was replaced with a floxed splice acceptor/neomycin resistance cassette and a modified exon 9 in which a G to A mutation results in the amino acid substitution of lysine for glutamic acid at position 545 (E545K). Cre-mediated recombination removed the selection cassette.
  • mutations:
  • Insertion,
  • Single point mutation
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories





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