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Allele : Tg(tetO-NRG1_i4)6Ajla transgene insertion 6, Amanda J Law

Primary Identifier	MGI:5784536	Allele Type	Transgenic
Attribute String	Humanized sequence, Inducible, Inserted expressed sequence	Gene	Tg(tetO-NRG1_i4)6Ajla
Strain of Origin	C57BL/6J	Induced With	doxycycline/tetracycline
Is Recombinase	false	Is Wild Type	false

molecularNote

The tetracycline responsive promoter drives inducible expression of the human isoform IV cDNA. Two lines, 6 and 13 were described. Line 6 is entered as the representative line.

mutations:
Insertion

synonyms:
NRGI-IV,
NRGI-IV

earliestPublication:
Papaleo F, et al. (2016) Behavioral, Neurophysiological, and Synaptic Impairment in a Transgenic Neuregulin1 (NRG1-IV) Murine Schizophrenia Model. J Neurosci 36(17):4859-75

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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