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Allele : Dmd<tm1Kmf> dystrophin, muscular dystrophy; targeted mutation 1, Kevin M Flanigan

Primary Identifier  MGI:5781149 Allele Type  Targeted
Attribute String  Hypomorph Gene  Dmd
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct inserted downstream of exon 2 a loxP site, a duplicate copy of exon 2 and an FRT-flanked neomycin resistance cassette with a 3' loxP site. mRNA analysis confirms the inclusion of a duplicated exon 2 in muscle. Immunofluorescence and immunoblot analysis indicate that expression is essentially absent, although some muscle shows very low-level trace expression.
  • mutations:
  • Duplication,
  • Insertion
  • synonyms:
  • Dup2,
  • Dup2
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories