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Allele : Col25a1<tm1.1Tiwa> collagen, type XXV, alpha 1; targeted mutation 1.1, Takeshi Iwatsubo

Primary Identifier	MGI:5781011	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Col25a1
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

An FRT-flanked beta-geo cassette replaced exon 2, which contains the furin cleavage site. Flp-mediated recombination removed the beta-geo cassette. Western blot analysis confirmed the absence of protein expression in E18.5 brains.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Tanaka T, et al. (2014) CLAC-P/collagen type XXV is required for the intramuscular innervation of motoneurons during neuromuscular development. J Neurosci 34(4):1370-9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

3 Carried By

0 Driven By

5 Publication categories

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