Primary Identifier | MGI:5781011 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Col25a1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An FRT-flanked beta-geo cassette replaced exon 2, which contains the furin cleavage site. Flp-mediated recombination removed the beta-geo cassette. Western blot analysis confirmed the absence of protein expression in E18.5 brains. |