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Allele : Ptger3<tm1.1Brey> prostaglandin E receptor 3 (subtype EP3); targeted mutation 1.1, Richard M Breyer

Primary Identifier  MGI:5784744 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptger3
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector contained a loxP-flanked neo selection cassette in intron 1 and the exon coding for the beta C-terminal variant replacing the gamma variant specific sequence at the 3' end of exon 2. A third loxP site was placed downstream of the beta exon. Subsequently, cre-mediated recombination removed the neo cassette and the remainder of exon 2 and the beta exon, creating an allele that knocks out all three (alpha, beta, gamma) splice variants.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • EP3<->,
  • EP3<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories