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Allele : Dusp8<tm1Jmol> dual specificity phosphatase 8; targeted mutation 1, Jeffery Molkentin
Primary Identifier  MGI:5788467 Allele Type  Targeted
Attribute String  Null/knockout Gene  Dusp8
Transmission  Germline Strain of Origin  129/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 5 and 6, encoding the catalytic domain, were replaced with a neomycin resistance cassette via homologous recombination. RT-PCR analysis confirmed the absence of mRNA in the heart, brain and lung.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Dusp8 KO,
  • Dusp8 KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

8 Publication categories





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