Primary Identifier | MGI:5788166 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inducible, Inserted expressed sequence | Gene | Tg(tetO-MAPT)32Lms |
Strain of Origin | C57BL/6 | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A transgenic construct containing cDNA of the human MAPT gene encoding the 1N4R isoform, with upstream intronic sequence (from pCI-neo vector) and a Kozak sequence, and downstream bovine growth hormone polyadenylation sequence, all under the control of the tetO, tetracycline-responsive regulatory element (TRE-tight). |