Primary Identifier | MGI:5789549 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Tlr4 |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced A to T transversion at base pair 66,839,303 (v38) on chromosome 4, or base pair 11,493 in the GenBank genomic region NC_000070 for the Tlr4 gene. The mutation corresponds to residue 613 in the mRNA sequence NM_021297.2 within exon 3 of 3 total exons. The mutation results in an asparagine (N) to isoleucine (I) substitution at position 111 (N111I) in the protein. |