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Allele : Nlrp3<M10Btlr> NLR family, pyrin domain containing 3; mutation 10, Bruce Beutler

Primary Identifier  MGI:5789569 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Nlrp3
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced C to T transition at base pair 59,548,010 (v38) on chromosome 11, or base pair 6,442 in the GenBank genomic region NC_000077. The mutation corresponds to residue 638 in the mRNA sequence NM_145827 within exon 4 of 10 total exons. The mutation results in substitution of arginine (R) 138 to a premature stop codon (R138*) in the protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Park7,
  • Park7
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele