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Allele : Cdkl5<tm2.1Joez> cyclin dependent kinase like 5; targeted mutation 2.1, Zhaolan Zhou
Primary Identifier  MGI:5790794 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Cdkl5
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a FRT-flanked neomycin resistance (neo) cassette downstream of exon 5, and a single nucleotide change of C to T, leading to a nonsense mutation at arginine 59 (R59X). Flp-mediated recombination removed the neo cassette.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • CDKL5 R59X,
  • CDKL5 R59X
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories





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