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Allele : Il17ra<tm1c(KOMP)Wtsi> interleukin 17 receptor A; targeted mutation 1c, Wellcome Trust Sanger Institute

Primary Identifier  MGI:5792909 Allele Type  Targeted
Attribute String  Conditional ready Gene  Il17ra
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
molecularNote  The L1L2_Bact_P cassette was inserted at position 120449477 of Chromosome 6 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 120451075. A "conditional ready" (floxed) allele was be created by flp recombinase expression in mice, resulting in an allele where loxP sites flank exons 3 and 4 of the gene.
  • mutations:
  • Insertion
  • synonyms:
  • Il17ra<F>,
  • Il17ra<F>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

6 Publication categories

Trail: Allele