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Allele : Kdm4a<tm1c(EUCOMM)Wtsi> lysine (K)-specific demethylase 4A; targeted mutation 1c, Wellcome Trust Sanger Institute

Primary Identifier  MGI:5792924 Allele Type  Targeted
Attribute String  Conditional ready Gene  Kdm4a
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
Project Collection  EUCOMM
molecularNote  The L1L2_Bact_P cassette was inserted at position 118032444 of Chromosome 4 upstream of exon 3 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 118033390. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice, deleting the lacZ sequence and neomycin selection cassette. LoxP sites flank exon 3.
  • mutations:
  • Insertion
  • synonyms:
  • Jmjd2a<f>,
  • Jmjd2a<f>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories