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Allele : Zmiz1<tm1c(EUCOMM)Hmgu> zinc finger, MIZ-type containing 1; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH

Primary Identifier  MGI:5795595 Allele Type  Targeted
Attribute String  Conditional ready Gene  Zmiz1
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  EUCOMM
molecularNote  The L1L2_Bact_P cassette was inserted at position 25644591 of Chromosome 14 upstream of exon 9 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the exon 9 at position 25645559. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice, resulting in the deletion of the lacZ sequence and neomycin selection cassette. The exon 9 remains flanked by loxP sites.
  • mutations:
  • Insertion
  • synonyms:
  • Zmiz1<f>,
  • Zmiz1<f>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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7 Publication categories