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Allele : Fan1<tm1c(KOMP)Wtsi> FANCD2/FANCI-associated nuclease 1; targeted mutation 1c, Wellcome Trust Sanger Institute

Primary Identifier  MGI:5796185 Allele Type  Targeted
Attribute String  Conditional ready Gene  Fan1
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
molecularNote  The L1L2_Bact_P cassette was inserted at position 64018509 of Chromosome 7 upstream of the exon 3 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon 4 at position 64021818. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele, deleting the lacZ and neomycin selection cassette and leaving loxP sites flanking exons 3 and 4.
  • mutations:
  • Insertion
  • synonyms:
  • Fan1lox,
  • Fan1lox
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories