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Allele : Tnf<Bpsm1> tumor necrosis factor; bone phenotype spontaneous mutation 1
Primary Identifier  MGI:5795894 Allele Type  Spontaneous
Gene  Tnf Inheritance Mode  Dominant
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A retrotransposon consisting of a small interspersed element (SINE) spontaneously inserted into the 3'UTR. This insertion provides a new polyadenylation signal and terminates the mRNA prematurely. Western blot analysis confirmed increased protein expression in bone marrow-derived macrophage lysates.
  • mutations:
  • Viral insertion
  • synonyms:
  • BPSM1<m>,
  • BPSM1<m>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories





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