| Primary Identifier | MGI:5796303 | Allele Type | Targeted |
| Attribute String | Conditional ready | Gene | Bmp2 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 124 base pair (bp) loxP site has replaced a PvuII restriction enzyme recognition site 76 bp past the translation termination codon, and a Pgk-neomycin phosphotransferase cassette flanked by frt sites and followed by a second loxP site has replaced an AccI recognition site 446 bp downstream of the stop codon. The loxP sites flank both the frt-flanked selection cassette and an ultraconserved sequence (UCS) in the 3' untranslated region (3'-UTR) of the mouse gene that mediates post-transcriptional repression of protein synthesis. |
